S71N (p.Ser71Asn) variant of TLR4 (Toll-like receptor 4)
S71N (p.Ser71Asn) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
S71N (p.Ser71Asn) variant details
- p.Ser71Asn
- gnomAD rs200606970
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.07
- CADD 17.90
- PolyPhen-2 0.49
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available