S55A (p.Ser55Ala) variant of TLR4 (Toll-like receptor 4)
S55A (p.Ser55Ala) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
S55A (p.Ser55Ala) variant details
- p.Ser55Ala
- gnomAD 9-117708632-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.13
- CADD 23.20
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available