S3T (p.Ser3Thr) variant of TLR4 (Toll-like receptor 4)
S3T (p.Ser3Thr) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data, published literature, and structural context.
S3T (p.Ser3Thr) variant details
- p.Ser3Thr
- gnomAD 9-117704479-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0497
- REVEL 0.00
- CADD 8.04
- PolyPhen-2 0.01
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available