R6H (p.Arg6His) variant of TLR4 (Toll-like receptor 4)
R6H (p.Arg6His) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
R6H (p.Arg6His) variant details
- p.Arg6His
- ExAC rs770810237
- gnomAD rs770810237
- Missense
- Variant Prioritization Score for Impact Estimate 0.147
- REVEL 0.03
- CADD 17.40
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the South Asian population (allele frequency 7e-05)
- Structural context available