R67K (p.Arg67Lys) variant of TLR4 (Toll-like receptor 4)
R67K (p.Arg67Lys) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
R67K (p.Arg67Lys) variant details
- p.Arg67Lys
- TOPMed rs1280345843
- gnomAD rs1280345843
- Missense
- Variant Prioritization Score for Impact Estimate 0.0975
- REVEL 0.10
- CADD 1.40
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available