R67G (p.Arg67Gly) variant of TLR4 (Toll-like receptor 4)
R67G (p.Arg67Gly) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
R67G (p.Arg67Gly) variant details
- p.Arg67Gly
- gnomAD 9-117708668-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.118
- REVEL 0.02
- CADD 18.60
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available