Q39H (p.Gln39His) variant of TLR4 (Toll-like receptor 4)
Q39H (p.Gln39His) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
Q39H (p.Gln39His) variant details
- p.Gln39His
- 1000Genomes rs201589239
- ExAC rs201589239
- TOPMed rs201589239
- gnomAD rs201589239
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- REVEL 0.15
- CADD 18.30
- PolyPhen-2 0.49
- SIFT 0.01
- Most common in the 1KG:MSL population (allele frequency 0.0063)
- Structural context available