P49P (p.Pro49Pro) variant of TLR4 (Toll-like receptor 4)
P49P (p.Pro49Pro) in TLR4 (Toll-like receptor 4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
P49P (p.Pro49Pro) variant details
- p.Pro49Pro
- rs375037549
- gnomAD 9-117708616-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.084
- CADD 0.48
- Most common in the HGDP:BOUGAINVILLE population (allele frequency 0.27)
- Structural context available
- Literature evidence available