P34T (p.Pro34Thr) variant of TLR4 (Toll-like receptor 4)
P34T (p.Pro34Thr) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
P34T (p.Pro34Thr) variant details
- p.Pro34Thr
- gnomAD 9-117708569-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.14
- CADD 22.50
- PolyPhen-2 0.24
- SIFT 0.05
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available