P23T (p.Pro23Thr) variant of TLR4 (Toll-like receptor 4)
P23T (p.Pro23Thr) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
P23T (p.Pro23Thr) variant details
- p.Pro23Thr
- TOPMed rs1191926239
- gnomAD rs1191926239
- Missense
- Variant Prioritization Score for Impact Estimate 0.104
- REVEL 0.05
- CADD 15.80
- PolyPhen-2 0.01
- SIFT 0.18
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available