P13L (p.Pro13Leu) variant of TLR4 (Toll-like receptor 4)
P13L (p.Pro13Leu) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P13L (p.Pro13Leu) variant details
- p.Pro13Leu
- ExAC rs775509862
- gnomAD rs775509862
- Missense
- Variant Prioritization Score for Impact Estimate 0.162
- REVEL 0.06
- CADD 20.70
- PolyPhen-2 0.01
- SIFT 0.82
- Most common in the South Asian population (allele frequency 0.0001)
- Structural context available