N51S (p.Asn51Ser) variant of TLR4 (Toll-like receptor 4)
N51S (p.Asn51Ser) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
N51S (p.Asn51Ser) variant details
- p.Asn51Ser
- gnomAD 9-117708621-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.108
- REVEL 0.02
- CADD 13.50
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available