N51K (p.Asn51Lys) variant of TLR4 (Toll-like receptor 4)
N51K (p.Asn51Lys) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
N51K (p.Asn51Lys) variant details
- p.Asn51Lys
- ESP rs148151027
- ExAC rs148151027
- TOPMed rs148151027
- gnomAD rs148151027
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.04
- CADD 15.00
- PolyPhen-2 0.10
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available