N44H (p.Asn44His) variant of TLR4 (Toll-like receptor 4)
N44H (p.Asn44His) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
N44H (p.Asn44His) variant details
- p.Asn44His
- TOPMed rs1235644534
- gnomAD rs1235644534
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- REVEL 0.20
- CADD 24.60
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available