N35K (p.Asn35Lys) variant of TLR4 (Toll-like receptor 4)
N35K (p.Asn35Lys) in TLR4 (Toll-like receptor 4) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
N35K (p.Asn35Lys) variant details
- p.Asn35Lys
- gnomAD 9-117708573-AT-A
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.471
- CADD 16.80
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available