M15V (p.Met15Val) variant of TLR4 (Toll-like receptor 4)
M15V (p.Met15Val) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
M15V (p.Met15Val) variant details
- p.Met15Val
- ExAC rs202028525
- TOPMed rs202028525
- gnomAD rs202028525
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.04
- CADD 22.20
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available