M15L (p.Met15Leu) variant of TLR4 (Toll-like receptor 4)
M15L (p.Met15Leu) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
M15L (p.Met15Leu) variant details
- p.Met15Leu
- ExAC rs202028525
- TOPMed rs202028525
- gnomAD rs202028525
- Missense
- Variant Prioritization Score for Impact Estimate 0.209
- REVEL 0.13
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available