L61P (p.Leu61Pro) variant of TLR4 (Toll-like receptor 4)
L61P (p.Leu61Pro) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
L61P (p.Leu61Pro) variant details
- p.Leu61Pro
- gnomAD 9-117708651-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.654
- REVEL 0.65
- CADD 27.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available