L59P (p.Leu59Pro) variant of TLR4 (Toll-like receptor 4)
L59P (p.Leu59Pro) in TLR4 (Toll-like receptor 4) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
L59P (p.Leu59Pro) variant details
- p.Leu59Pro
- gnomAD 9-117708642-A-ACC
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.415
- CADD 23.40
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available
- Literature evidence available