L52I (p.Leu52Ile) variant of TLR4 (Toll-like receptor 4)
L52I (p.Leu52Ile) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
L52I (p.Leu52Ile) variant details
- p.Leu52Ile
- gnomAD 9-117708623-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.05
- CADD 4.67
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available