L11V (p.Leu11Val) variant of TLR4 (Toll-like receptor 4)
L11V (p.Leu11Val) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
L11V (p.Leu11Val) variant details
- p.Leu11Val
- gnomAD 9-117704503-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.13
- CADD 22.00
- PolyPhen-2 0.33
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available