K47R (p.Lys47Arg) variant of TLR4 (Toll-like receptor 4)
K47R (p.Lys47Arg) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
K47R (p.Lys47Arg) variant details
- p.Lys47Arg
- Ensembl rs1829177362
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.02
- CADD 15.60
- PolyPhen-2 0.01
- SIFT 0.38
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available