I36V (p.Ile36Val) variant of TLR4 (Toll-like receptor 4)
I36V (p.Ile36Val) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
I36V (p.Ile36Val) variant details
- p.Ile36Val
- ExAC rs749333850
- TOPMed rs749333850
- gnomAD rs749333850
- Missense
- Variant Prioritization Score for Impact Estimate 0.0758
- REVEL 0.06
- CADD 5.50
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available