I36S (p.Ile36Ser) variant of TLR4 (Toll-like receptor 4)
I36S (p.Ile36Ser) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
I36S (p.Ile36Ser) variant details
- p.Ile36Ser
- gnomAD 9-117708576-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.07
- CADD 15.80
- PolyPhen-2 0.02
- SIFT 0.08
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available