H68P (p.His68Pro) variant of TLR4 (Toll-like receptor 4)
H68P (p.His68Pro) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
H68P (p.His68Pro) variant details
- p.His68Pro
- gnomAD 9-117708672-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.20
- CADD 9.51
- PolyPhen-2 0.40
- SIFT 0.20
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available
- Literature evidence available