H68D (p.His68Asp) variant of TLR4 (Toll-like receptor 4)
H68D (p.His68Asp) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
H68D (p.His68Asp) variant details
- p.His68Asp
- ExAC rs762574594
- gnomAD rs762574594
- Missense
- Variant Prioritization Score for Impact Estimate 0.127
- REVEL 0.11
- CADD 9.95
- PolyPhen-2 0.13
- SIFT 0.20
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available