G70G (p.Gly70Gly) variant of TLR4 (Toll-like receptor 4)
G70G (p.Gly70Gly) in TLR4 (Toll-like receptor 4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
G70G (p.Gly70Gly) variant details
- p.Gly70Gly
- rs958681405
- gnomAD 9-117708679-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.465
- CADD 6.23
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available