E42E (p.Glu42Glu) variant of TLR4 (Toll-like receptor 4)
E42E (p.Glu42Glu) in TLR4 (Toll-like receptor 4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
E42E (p.Glu42Glu) variant details
- p.Glu42Glu
- rs1209407592
- gnomAD 9-117708595-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.119
- CADD 5.46
- Most common in the South Asian population (allele frequency 4.6e-05)
- Structural context available
- Literature evidence available