E27V (p.Glu27Val) variant of TLR4 (Toll-like receptor 4)
E27V (p.Glu27Val) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
E27V (p.Glu27Val) variant details
- p.Glu27Val
- gnomAD rs1186652911
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.13
- CADD 29.80
- PolyPhen-2 0.16
- SIFT 0.05
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available