E27D (p.Glu27Asp) variant of TLR4 (Toll-like receptor 4)
E27D (p.Glu27Asp) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
E27D (p.Glu27Asp) variant details
- p.Glu27Asp
- cosmic curated COSV62923
- Missense
- Variant Prioritization Score for Impact Estimate 0.108
- REVEL 0.13
- CADD 0.10
- PolyPhen-2 0.00
- SIFT 0.80
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available