E24D (p.Glu24Asp) variant of TLR4 (Toll-like receptor 4)
E24D (p.Glu24Asp) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
E24D (p.Glu24Asp) variant details
- p.Glu24Asp
- Ensembl rs1829103238
- Missense
- Variant Prioritization Score for Impact Estimate 0.203
- REVEL 0.03
- CADD 21.60
- PolyPhen-2 0.01
- SIFT 0.43
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available