D60G (p.Asp60Gly) variant of TLR4 (Toll-like receptor 4)
D60G (p.Asp60Gly) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
D60G (p.Asp60Gly) variant details
- p.Asp60Gly
- gnomAD 9-117708648-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.558
- REVEL 0.49
- CADD 27.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available