C29Y (p.Cys29Tyr) variant of TLR4 (Toll-like receptor 4)
C29Y (p.Cys29Tyr) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
C29Y (p.Cys29Tyr) variant details
- p.Cys29Tyr
- TOPMed rs1829103501
- Missense
- Variant Prioritization Score for Impact Estimate 0.52
- REVEL 0.44
- CADD 28.40
- PolyPhen-2 0.99
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available