C29R (p.Cys29Arg) variant of TLR4 (Toll-like receptor 4)
C29R (p.Cys29Arg) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
C29R (p.Cys29Arg) variant details
- p.Cys29Arg
- gnomAD 9-117704557-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.568
- REVEL 0.56
- CADD 29.90
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available