C20P (p.Cys20Pro) variant of TLR4 (Toll-like receptor 4)
C20P (p.Cys20Pro) in TLR4 (Toll-like receptor 4) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
C20P (p.Cys20Pro) variant details
- p.Cys20Pro
- rs1564261927
- gnomAD 9-117704523-C-CCT
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.268
- CADD 24.50
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available