C20C (p.Cys20Cys) variant of TLR4 (Toll-like receptor 4)
C20C (p.Cys20Cys) in TLR4 (Toll-like receptor 4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
C20C (p.Cys20Cys) variant details
- p.Cys20Cys
- rs374086120
- gnomAD 9-117704532-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.255
- CADD 14.40
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available
- Literature evidence available