A4S (p.Ala4Ser) variant of TLR4 (Toll-like receptor 4)
A4S (p.Ala4Ser) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data, published literature, and structural context.
A4S (p.Ala4Ser) variant details
- p.Ala4Ser
- gnomAD 9-117704482-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0486
- REVEL 0.01
- CADD 0.48
- PolyPhen-2 0.00
- SIFT 0.51
- Population evidence available
- Structural context available
- Literature evidence available