A4A (p.Ala4Ala) variant of TLR4 (Toll-like receptor 4)
A4A (p.Ala4Ala) in TLR4 (Toll-like receptor 4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
A4A (p.Ala4Ala) variant details
- p.Ala4Ala
- rs1389577268
- gnomAD 9-117704484-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.109
- CADD 3.96
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available
- Literature evidence available