A16S (p.Ala16Ser) variant of TLR4 (Toll-like receptor 4)
A16S (p.Ala16Ser) in TLR4 (Toll-like receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A16S (p.Ala16Ser) variant details
- p.Ala16Ser
- cosmic curated COSV10079
- gnomAD rs796659471
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.03
- CADD 23.20
- PolyPhen-2 0.17
- SIFT 0.09
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available