Y9C (p.Tyr9Cys) variant of TLR3 (Toll-like receptor 3)
Y9C (p.Tyr9Cys) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
Y9C (p.Tyr9Cys) variant details
- p.Tyr9Cys
- gnomAD rs1252260733
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- REVEL 0.09
- MetaLR 0.06
- MetaSVM -0.97
- CADD 4.53
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available