W11G (p.Trp11Gly) variant of TLR3 (Toll-like receptor 3)
W11G (p.Trp11Gly) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
W11G (p.Trp11Gly) variant details
- p.Trp11Gly
- gnomAD 4-186076650-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.12
- MetaLR 0.04
- MetaSVM -1.03
- CADD 10.10
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available