V55L (p.Val55Leu) variant of TLR3 (Toll-like receptor 3)
V55L (p.Val55Leu) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
V55L (p.Val55Leu) variant details
- p.Val55Leu
- gnomAD rs1222090489
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.05
- MetaLR 0.09
- MetaSVM -1.04
- CADD 15.30
- PolyPhen-2 0.03
- SIFT 0.30
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available