V45E (p.Val45Glu) variant of TLR3 (Toll-like receptor 3)
V45E (p.Val45Glu) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
V45E (p.Val45Glu) variant details
- p.Val45Glu
- gnomAD rs2099302521
- Missense
- Variant Prioritization Score for Impact Estimate 0.481
- REVEL 0.43
- MetaLR 0.35
- MetaSVM -0.09
- CADD 24.10
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available