V34A (p.Val34Ala) variant of TLR3 (Toll-like receptor 3)
V34A (p.Val34Ala) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
V34A (p.Val34Ala) variant details
- p.Val34Ala
- gnomAD 4-186076720-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.07
- MetaLR 0.05
- MetaSVM -0.99
- CADD 0.74
- PolyPhen-2 0.00
- SIFT 0.96
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available