T72I (p.Thr72Ile) variant of TLR3 (Toll-like receptor 3)
T72I (p.Thr72Ile) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
T72I (p.Thr72Ile) variant details
- p.Thr72Ile
- ExAC rs760739824
- gnomAD rs760739824
- Missense
- Variant Prioritization Score for Impact Estimate 0.451
- REVEL 0.28
- MetaLR 0.38
- MetaSVM -0.36
- CADD 20.60
- PolyPhen-2 0.30
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.3e-05)
- Structural context available