T54A (p.Thr54Ala) variant of TLR3 (Toll-like receptor 3)
T54A (p.Thr54Ala) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
T54A (p.Thr54Ala) variant details
- p.Thr54Ala
- Ensembl rs2150066317
- Missense
- Variant Prioritization Score for Impact Estimate 0.384
- REVEL 0.25
- MetaLR 0.20
- MetaSVM -0.77
- CADD 24.00
- PolyPhen-2 0.70
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available