T51R (p.Thr51Arg) variant of TLR3 (Toll-like receptor 3)
T51R (p.Thr51Arg) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
T51R (p.Thr51Arg) variant details
- p.Thr51Arg
- gnomAD rs1342269987
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -1.03
- CADD 3.35
- PolyPhen-2 0.01
- SIFT 0.66
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available