T4A (p.Thr4Ala) variant of TLR3 (Toll-like receptor 3)
T4A (p.Thr4Ala) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
T4A (p.Thr4Ala) variant details
- p.Thr4Ala
- gnomAD 4-186076629-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0807
- REVEL 0.05
- MetaLR 0.03
- MetaSVM -1.04
- CADD 0.00
- PolyPhen-2 0.01
- SIFT 0.79
- Population evidence available
- Structural context available
- Literature evidence available