T43S (p.Thr43Ser) variant of TLR3 (Toll-like receptor 3)
T43S (p.Thr43Ser) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
T43S (p.Thr43Ser) variant details
- p.Thr43Ser
- gnomAD 4-186076747-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.32
- MetaLR 0.34
- MetaSVM -0.64
- CADD 8.24
- PolyPhen-2 0.00
- SIFT 0.81
- Population evidence available
- Structural context available
- Literature evidence available