T29P (p.Thr29Pro) variant of TLR3 (Toll-like receptor 3)
T29P (p.Thr29Pro) in TLR3 (Toll-like receptor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
T29P (p.Thr29Pro) variant details
- p.Thr29Pro
- gnomAD 4-186076704-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.123
- REVEL 0.10
- MetaLR 0.12
- MetaSVM -1.00
- CADD 5.73
- PolyPhen-2 0.07
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available